Read this new article: http://www.nybooks.com/articles/archives/2013/nov/07/physics-what-we-do-and-dont-know/ Weinberg is embracing the anthropic nonsense and writes that there is no explanation for the fundamental constants.
Weinberg, an actual scientist who once was an example to many, is publicly making the statement that for something there is no explanation. What a sad story.
This is the sadness of seeing death into the eye. That sadness induces him to say: "Because I did not find the explanation for the fundamental constants, nobody else will."